Contact

Liver transplantation

Introduction

In the context of a growing increase in chronic diseases and liver cancer, liver surgery and transplantation represent a major curative therapeutic option. Because of the severity of the underlying liver disease, surgical care remains difficult and not all patients registered for transplantation are able to receive a liver transplant.

Optimising the conditions of access to transplantation and surgical techniques is a major challenge for patients with severe liver disease.

Objectives

  • To develop new predictive models for prioritising patients on the waiting list for a liver transplant.
  • To study the mechanisms underlying the two major postoperative liver injuries: ischaemia-reperfusion injury and haemodynamic dysfunction.
  • To identify biomarkers for predicting the severity and outcome of these complications.
  • Evaluate treatment strategies to mitigate these lesions and improve short- and long-term outcomes for patients.
  • Develop new methods for optimising and preserving liver grafts to improve patient access to transplantation and transplant outcomes.

Strategy

Projects

No results found.

Publications

2018 Jun -

J Hepatol

PMID : 29410287

No-touch multibipolar radiofrequency ablation vs. surgical resection for solitary hepatocellular carcinoma ranging from 2 to 5 cm

Mohkam et al.

Télécharger

2020 May -

New England J Med

PMID : 32402160

Atezolizumab plus Bevacizumab in Unresectable Hepatocellular Carcinoma

Finn RS et al.

Télécharger

Make a donation is above all
speeding up research

Make a donation

Other areas of research

Viral Liver Disease

Viral liver diseases are caused by 5 main types of viruses (A, B, C, D and E). Although these viruses all cause liver disease, the severity, course and treatments depend on the virus.
Find out more

Liver Metabolism – MASLD

Metabolic dysfunction-associated steatotic liver disease (MASLD) is the most widespread chronic liver disease and continues to increase.
Find out more

Addiction and the liver

Liver diseases linked to addiction (alcohol, drug use) represent a major public health issue. Understanding, treating and developing appropriate treatments requires specific support for these often vulnerable patients.
Find out more

Hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related death worldwide. The majority of HCCs are associated with chronic liver disease due to chronic viral hepatitis, excessive alcohol consumption or metabolic disease.
Find out more

End-stage liver disease

All types of liver disease can develop into advanced pathology, with complications of varying degrees of severity, requiring rapid, specific treatment.
Find out more
Centre intégré des maladies du foie
Contact
Email : contact@ihu-hepatolyon.fr

Support IHL

Institut d’hépatologie de Lyon, 2023