Approximately 10% of the world population is exposed to a risk of alcohol-related liver disease (ALD) due to excessive alcohol consumption. This persistent liver injury can eventually lead to progressive fibrosis and cirrhosis, as well as the development of hepatocellular carcinoma. In addition, individuals with ALD may present with acute complications such as alcoholic hepatitis (AAH), in which a rapid diagnosis and severity stratification are key. AAH pathogenesis and severity have been linked to the composition of the gut microbiota and to the translocation of bacterial products and live bacteria from the gut to the portal blood which can reach the liver.
The main objectives of this research axis are:
No results found.
2023 Dec -
Durg Alcohol Rev
Hepatitis C virus cure from direct-acting antivirals and mortality: Are people with and without a history of injection drug use in the same boat?
Barré et al.
2023 Jul -
iScience
PMID : 37575179
Circulating microRNAs improve bacterial infection diagnosis and overall survival prediction in acute decompensation of liver cirrhosis
Chouik et al.
Institut d’hépatologie de Lyon, 2023
